ZOSTUM INJECTION 3GM (CEFOPERAZONE-2000MG + SULBACTAM-1000MG)
| COUNTRY OF ORIGIN | India |
|---|---|
| DOSAGE FORM | Injection |
| GENERIC NAME | Cefoperazone and Sulbactum |
| INDICATION | Bacterial infections |
| PACKAGING | 3 gm Injection in 1 Vial |
| MANUFACTURER | Zuventus Healthcare Ltd |
| COMPOSITION | CEFOPERAZONE-2000MG + SULBACTAM-1000MG |
ZOSTUM INJECTION 3GM belongs to the group of medicines called antibiotics used to treat various bacterial infections such as respiratory tract (lungs) infection, urine infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. ZOSTUM INJECTION 3GM does not work against infections caused by the virus, including cold and flu. ZOSTUM INJECTION 3GM is a combination of two antibiotics, namely: Cefoperazone (cephalosporin antibiotic) and sulbactam (beta-lactamase inhibitor). Cefoperazone works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria. On the other hand, sulbactam works by decreasing bacterial resistance and enhancing the activity of cefoperazone against the bacteria. Together, ZOSTUM INJECTION 3GM helps to treat bacterial infections. Take ZOSTUM INJECTION 3GM as prescribed by your doctor. You are advised to take ZOSTUM INJECTION 3GM for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience diarrhoea, allergic reaction, abnormal liver function tests, and anaemia (low number of red blood cells). Most of these side effects of ZOSTUM INJECTION 3GM do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Before starting ZOSTUM INJECTION 3GM, please inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take ZOSTUM INJECTION 3GM on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking ZOSTUM INJECTION 3GM if you are pregnant or planning for pregnancy. Avoid taking ZOSTUM INJECTION 3GM if you are breastfeeding as ZOSTUM INJECTION 3GM may pass into breast milk. Avoid alcohol consumption while taking ZOSTUM INJECTION 3GM to prevent unpleasant side-effects.
Uses of ZOSTUM INJECTION 3GM
Bacterial infections.
Medicinal Benefits
ZOSTUM INJECTION 3GM belongs to the group of medicines called antibiotics used to treat various bacterial infections such as respiratory tract (lungs) infection, urine infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections. ZOSTUM INJECTION 3GM is a combination of two antibiotics, namely: Cefoperazone (cephalosporin antibiotic) and sulbactam (beta-lactamase inhibitor). Cefoperazone works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria. On the other hand, sulbactam works by decreasing bacterial resistance and enhancing the activity of cefoperazone against the bacteria. Together, ZOSTUM INJECTION 3GM helps to treat bacterial infections.
Directions for Use
Storage
Side Effects of ZOSTUM INJECTION 3GM
- Diarrhoea
- Allergic reaction
- Abnormal liver function tests
- Anaemia (low number of red blood cells)
In-Depth Precautions and Warning
Drug Warnings
After taking ZOSTUM INJECTION if you have allergy-like symptoms including rash, swelling of the face/lips/throat, difficulty in breathing, or tightness in the chest, immediately contact your doctor. Do not take ZOSTUM INJECTION 3GM if you have an allergy to ZOSTUM INJECTION, cephalosporins penicillin class of antibiotics as it may cause a skin rash, itching, and difficulty in breathing. People having liver disease or jaundice (yellowing of skin/eye) should not take ZOSTUM INJECTION 3GM, as it can damage your liver severely. You may have diarrhoea in some cases which can be managed by taking it with any probiotics and plenty of fluids. Do not take antacids along with ZOSTUM INJECTION; maintain a gap of 2-3 hours between both. Avoid alcohol consumption while taking ZOSTUM INJECTION to prevent unpleasant side-effects. ZOSTUM INJECTION may cause dizziness, so be cautious while driving. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side-effects.
Drug Interactions
Drug-Drug Interactions: ZOSTUM INJECTION may have interaction with a diuretic (furosemide), anticoagulants (warfarin), other antibiotics (gentamicin).
Food-Drug Interactions: No interactions found/established.
Drug-disease interactions: ZOSTUM INJECTION may have interactions with colitis (inflammation in the lining of the colon), seizures, dialysis, kidney, and liver dysfunction.
Safety Advice
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ALCOHOL
Avoid consuming alcohol while taking ZOSTUM INJECTION as it cause increased side effects.
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PREGNANCY
Please consult your doctor if you are pregnant, your doctor will prescribe ZOSTUM INJECTION only if the benefits outweigh the risks.
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BREAST FEEDING
A small amount of ZOSTUM INJECTION may pass into breast milk. Avoid taking ZOSTUM INJECTION if you are breastfeeding unless prescribed.
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DRIVING
ZOSTUM INJECTION may cause dizziness in some people, so it may affect your ability to drive.
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LIVER
Dose adjustment may be needed. Please consult your doctor before taking ZOSTUM INJECTION if you have liver impairment/liver disease.
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KIDNEY
Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking ZOSTUM INJECTION.
Habit Forming
Diet & Lifestyle Advise
- Probiotics should be taken after taking the full course of ZOSTUM INJECTION in order to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help to restore the good bacteria of the intestine.
- Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet.
- Avoid intake of alcoholic beverages with ZOSTUM INJECTION as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the ZOSTUM INJECTION in fighting off infections.
Special Advise
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection harder to treat.
- Discontinue ZOSTUM INJECTION and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
- Diarrhoea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
- ZOSTUM INJECTION is preferably taken with food to avoid an upset stomach.
- Some people may be allergic to ZOSTUM INJECTION or other penicillin or cephalosporin group of antibiotics. So a prior sensitivity test may be necessary. Inform your doctor if you are allergic to any medicine particularly antibiotics belong to these groups.
- If you feel nauseous after taking ZOSTUM INJECTION, stick to simple meals like porridge, khichdi, dal roti, and other home-cooked meals. Avoid spicy and fatty food.
Other Information (ZOS0029)
This item is Not Returnable.
Expires on or after – Sep-2022
Patients Concern
Disease/Condition Glossary
Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly of spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.
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