Virofix ( Ribavirin)is used in combination with other antiviral medications to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.
Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.
Virofix ( Ribavirin)works by reducing the amount of hepatitis C virus in your body, which may help your liver recover.
Mechanism of action:
Virofix ( Ribavirin)is readily phosphorylated intracellularly by adenosine kinase to Virofix ( Ribavirin)mono-, di-, and triphosphate metabolites.
Virofix ( Ribavirin)triphosphate (RTP) is a potent competitive inhibitor of inosine monophosphate (IMP) dehydrogenase, viral RNA polymerase and messenger RNA (mRNA) guanylyltransferase (viral) and can be incorporated into RNA in RNA viral species..
Guanylyltranserase inhibition stops the capping of mRNA.
These diverse effects result in a marked reduction of intracellular guanosine triphosphate (GTP) pools and inhibition of viral RNA and protein synthesis.
Virofix ( Ribavirin)is also incorporated into the viral genome causing lethal mutagenesis and a subsequent decrease in specific viral infectivity.
All medicines may cause side effects, but many people have no, or minor, side effects.
Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea; dizziness; dry mouth; dry skin; hair loss; joint pain; loss of appetite; mild headache, nausea, or vomiting; mild stomach pain; tiredness; trouble sleeping; upset stomach; weakness or fatigue.
Before taking Virofix ( Ribavirin), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Talk to your pharmacist for more details.
Store Virofix ( Ribavirin) between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Virofix ( Ribavirin)out of the reach of children and away from pets.