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Cimivir Tabltes

$77.83

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Description

Product Details:

Minimum Order Quantity 3 Bottle
Dosage Form Tablet
Dose/Strength 400 mg
Packaging Size 28 Tablets

Indication:

  • It is used for the treatment of hepatitis Cvirus (HCV) infection.
  • Compared to previous treatments, Cimivir (Sofosbuvir )-based regimens provide a higher cure rate, fewer side effects, and a two- to four-fold reduced duration of therapy.
  • Cimivir (Sofosbuvir ) allows most patients to be treated successfully without the use of peginterferon,an injectable drug with severe side effects.
  • that is a key component of older drug combinations for the treatment of HCV.Cimivir (Sofosbuvir ) is used for the treatment of chronic hepatitis C, genotypes 1, 2, 3, and 4, in combination with pegylated interferon and ribavirin, or with ribavirin alone.
  • It is also used in combination with the viral NS5a inhibitor ledipasvir in an interferon-free combination for the treatment of genotype 1 hepatitis C infection.
  • Cimivir (Sofosbuvir ) is also used in HCV patients with an HIV coinfection.
  • The treatment is based on a number of clinical trials, for example the ELECTRON trial which showed that a dual interferon-free regimen of Cimivir (Sofosbuvir ) plus ribavirin produced a 24-week post-treatment sustained virological response (SVR24) rate of 100% for previously untreated patients with HCV genotypes 2 or 3.


Mechanism of action:

  • Cimivir (Sofosbuvir ) contains oral nucleotide analog inhibitor of the hepatitis C virus (HCV) polymerase.
  • The drug is a direct-acting antiviral agent and interferes straight with the HCV lifecycle, restraining the viral replication.
  • It can be incorporated into HCV RNA by the NS5B polymerase and acts as a chain terminator. The drug is available for oral use in the form of 400mg tablets.


Dosage and Administration:

  • The recommended daily dose of Cimivir (Sofosbuvir ) is 400mg tablet to be taken once daily with or without food. Cimivir (Sofosbuvir ) should be used in combination with Ribavirin or in combination with Pegylated Interferon and Ribavirin for the treatment of CHC (Chronic Hepatitis C) in adults.
  • It is highly advisable to administer the drug under strict medical supervision and advice.


Side effects:

  • Adverse events associated with the use of Cimivir (Sofosbuvir ) in combination with Ribavirin may include, but are not limited to, the followingo Fatigue , headacheAdverse events associated with the use of Cimivir (Sofosbuvir ) in combination with Peginterferon Alfa and Ribavirin may include, but are not limited to, the following:o fatigue,headache, nausea, insomnia, anemia

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